Provigil Structure is an agent with a rapidly expanding list of off-label uses in neurology, medicine, and psychiatry. It appears to have multiple effects on catecholamine systems in the brain, including DAT and NET inhibition, and elevation of extracellular catecholamines, glutamate, serotonin, and HA, activation of the orexinergic system, and decreased GABA.
Alpha-adrenergic, D1 and D2 receptors in the brain mediate modafinil effects on waking and activity, and may also mediate the neurochemical effects on these other neurotransmitter systems. Modafinil is also significantly different from amphetamine in structure https://topmodafinilrxpills.com/6-cost-for-provigil-buwat.php profile of neurochemical and behavioral effects.
Intriguing preliminary evidence suggests that modafinil may be relatively selective for cortical over subcortical effects. In the clinical setting, modafinil shows efficacy in a number of neurological and psychiatric illnesses, with a significantly improved side-effect profile compared to amphetamine, including a relatively low liability to abuse. Equally important, there is now increasing evidence that modafinil can improve cognitive function, particularly working memory, episodic memory, and processes requiring cognitive control.
Studies in animal models and neuroimaging in humans suggest that these effects may be related to specific actions of modafinil in the frontal cortex. The remediation of cognitive dysfunction and related neural activity may in turn form the basis of the clinical efficacy of this agent, across a range of neuropsychiatric disorders. Further investigation is necessary to confirm these initial findings, to identify specificity of these effects in the domains of neurochemistry, neuroanatomy, and cognition, and to evaluate other factors relevant to clinical use, such as Provigil Structure relationship of single-dose to sustained dosing regimens, and the relationship of pro-cognitive effects to clinical outcome.
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Phasic not tonic pupillary responses vary with auditory vigilance performance. Psychophysiology 19 : — Beatty J b. Task-evoked pupillary responses, processing load, and the structure of processing resources. Psychol Bull 91 : — First evidence of a delay-dependent working memory-enhancing effect of modafinil in mice.
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Modafinil: A Review of Neurochemical Actions and Effects on Cognition
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Modafinil, sold under the brand name Provigil among others, is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. Provigil is used to treat sleepiness caused by sleep apnea or narcolepsy. Learn about side effects, interactions and indications.
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Fierce Healthcare. Archived from the Provigil Structure on May 24, Retrieved June 7, June 23, Federal Commission for Protection against Health Risks.PROVIGIL (modafinil) is a wakefulness-promoting agent for oral administration. Modafinil is a racemic compound. The chemical name for modafinil is. Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy.
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Modafinil, sold under the brand name Provigil among others, is a medication to treat sleepiness due to narcolepsy, shift work sleep. PROVIGIL (modafinil) is a wakefulness-promoting agent for oral administration. Modafinil is a racemic compound. The chemical name for modafinil is 2-[.